کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4339559 1295760 2010 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Estrogen receptors in the central auditory system of male and female mice
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
Estrogen receptors in the central auditory system of male and female mice
چکیده انگلیسی
The estrogen receptors in the central auditory system of male and female mice were characterized using immunocytochemical methods. Estrogen receptors α and β (ERα, ERβ) were localized predominantly in the ventral cochlear nucleus, nucleus of the trapezoid body, the lateral- and medio-ventral periolivary nuclei, the dorsal lateral lemniscus, and the inferior colliculus. The medial geniculate nucleus was negative for both ERα and ERβ whereas the auditory cortex was positive for ERα. The lateral superior olive, the ventral lateral lemniscus and the central nucleus of the inferior colliculus expressed only ERβ. The differential localization of ERα and ERβ may indicate distinct roles for these two receptors in auditory processing. No major differences in the pattern, number or intensity of receptor expression was found between male and female animals. The comprehensive anatomic map that is constructed for ERα and ERβ in the central auditory pathway will be a useful foundation to elucidate the complexity of estrogen actions in the auditory system.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience - Volume 165, Issue 3, 3 February 2010, Pages 923-933
نویسندگان
, ,