کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4343457 1615101 2015 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Transcranial direct current stimulation over prefrontal cortex diminishes degree of risk aversion
ترجمه فارسی عنوان
تحریک جریان مستقیم ترانس کرانانیال در قشر پیش از قاعدگی باعث کاهش میزان ریسک پذیری در ریسک می شود
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب (عمومی)
چکیده انگلیسی


• Modulation of DLPFC by tDCS changed degree of risk aversion.
• A risk-measurement table was designed for testing risk preference.
• A within-subject design was adopted for boosting statistical power.
• Sham stimulation was highly influenced by wealth effect.
• Gender differences were found in risk averse response style.

Previous studies have established that transcranial direct current stimulation (tDCS) is a powerful technique for manipulating the activity of the human cerebral cortex. Many studies have found that weighing the risks and benefits in decision-making involves a complex neural network that includes the dorsolateral prefrontal cortex (DLPFC). We studied whether participants change the balance of risky and safe responses after receiving tDCS applied over the right and left prefrontal cortex. A total of 60 healthy volunteers performed a risk task while they received either anodal tDCS over the right prefrontal cortex, with cathodal over the left; anodal tDCS over the left prefrontal cortex, with cathodal over the right; or sham stimulation. The participants tended to choose less risky options after receiving sham stimulation, demonstrating that the task might be highly influenced by the “wealth effect”. There was no statistically significant change after either right anodal/left cathodal or left anodal/right cathodal tDCS, indicating that both types of tDCS impact the participants’ degrees of risk aversion, and therefore, counteract the wealth effect. We also found gender differences in the participants’ choices. These findings extend the notion that DLPFC activity is critical for risk decision-making. Application of tDCS to the right/left DLPFC may impact a person’s attitude to taking risks.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience Letters - Volume 598, 26 June 2015, Pages 18–22
نویسندگان
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