Expression of the P/Q (Cav2.1) calcium channel in nodose sensory neurons and arterial baroreceptors

► We evaluated the presence of P/Q type calcium channel in nodose sensory neurons. ► The P/Q-type channel supplies the major calcium current in subset of large neurons. ► This contrasts the majority of nodose cells where N-type channels predominate. ► We postulate a dominate P/Q channel preserves a high fidelity signal at the synapse.