Differential alterations of GABAA receptor (α1, β2, γ2 subunit) expression and increased seizure susceptibility in rat offspring from morphine-addicted mothers: Beneficial effect of dextromethorphan

▶ Prenatal morphine exposure increases seizure susceptibility in rat offspring. ▶ Prenatal morphine exposure alters subunit compositions of GABAAR in rat offspring. ▶ Dextromethorphan acts against these alterations.