STAT5 regulates glioma cell invasion by pathways dependent and independent of STAT5 DNA binding

▶ STAT5 was constitutively activated in glioma tissues. ▶ STAT5 was not activated in U87 glioma cells. ▶p-STAT5 positively regulates glioma cell invasion. ▶ STAT5 promotes glioma cell invasion via pathways independent of STAT5 activation and DNA binding.