کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4348773 1296905 2008 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Correlation between anosognosia and regional cerebral blood flow in Alzheimer's disease
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
Correlation between anosognosia and regional cerebral blood flow in Alzheimer's disease
چکیده انگلیسی
The purpose of this study was to determine the brain regions associated with anosognosia in Alzheimer's disease (AD). Anosognosia for memory disturbance was assessed in 29 probable AD patients, based on the discrepancy between questionnaire scores of the patients and their caregivers. In I-123-IMP single photon emission computed tomography (SPECT), a significant association was found between anosognosia and decreased perfusion in the orbitofrontal cortex, using regression analysis. This result is consistent with the previous studies that have reported an association between frontal dysfunction and anosognosia, and further suggests that the orbitofrontal cortex specifically associates with anosognosia in AD within the frontal cortex.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience Letters - Volume 435, Issue 1, 11 April 2008, Pages 7-10
نویسندگان
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