کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4351254 | 1297012 | 2006 | 5 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: 5 Hz repetitive TMS increases anticipatory motor activity in the human cortex 5 Hz repetitive TMS increases anticipatory motor activity in the human cortex](/preview/png/4351254.png)
In the present study, we analyzed how high-frequency repetitive transcranial magnetic stimulation (rTMS) of the primary motor hand area (M1-Hand) shapes anticipatory motor activity in frontal areas as indexed by the contingent negative variation (CNV). Eight right-handed volunteers received real or sham 5 Hz rTMS at an intensity of 90% resting motor threshold (1500 stimuli per session). Real but not sham rTMS to left M1-Hand induced a site-specific increase in amplitude of the late component of the CNV at the electrode C3 overlaying the site of stimulation. The increase in pre-movement activity in the stimulated cortex may reflect an increase in facilitatory drive from connected motor areas, enhanced responsiveness of the stimulated cortex to these inputs or both.
Journal: Neuroscience Letters - Volume 392, Issue 3, 16 January 2006, Pages 221–225