کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4353702 1298491 2009 14 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Nanotechnological applications for the treatment of neurodegenerative disorders
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
Nanotechnological applications for the treatment of neurodegenerative disorders
چکیده انگلیسی

Nanotechnology employs engineered materials or devices that interact with biological systems at a molecular level and could revolutionize the treatment of neurodegenerative disorders (NDs) by stimulating, responding to and interacting with target sites to induce physiological responses while minimizing side-effects. Conventional drug delivery systems do not provide adequate cyto-architecture restoration and connection patterns that are essential for functional recovery in NDs, due to limitations posed by the restrictive blood–brain barrier. This review article provides a concise incursion into the current and future applications of nano-enabled drug delivery systems for the treatment of NDs, in particular Alzheimer's and Parkinson's diseases, and explores the application of nanotechnology in clinical neuroscience to develop innovative therapeutic modalities for the treatment of NDs.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Progress in Neurobiology - Volume 88, Issue 4, August 2009, Pages 272–285
نویسندگان
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