Keywords: سد خونی مغزی; ARE, antioxidant response element; BBB, blood–brain barrier; FCCP, carbonilcyanide p-triflouromethoxyphenylhydrazone; Keap1, Kelch-like ECH-associated protein 1; Nrf2, nuclear factor E2-related factor 2; OCR, oxygen consumption rate; pMCAO, permanent midd
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Keywords: سد خونی مغزی; ASD, autism spectrum disorders; BBB, blood–brain barrier; BDNF, brain-derived neurotrophic factor; CRF, corticotropin-releasing factor; EGCG, epigallocatechin gallate; mTOR, mammalian target of rapamycin; mt, mitochondrial; NT, neurotensin; NTS, neurotens
Keywords: سد خونی مغزی; CNS, central nervous system; DIPG, diffuse intrinsic pontine gliomas; BBB, blood–brain barrier; CED, convection-enhanced delivery; HESC, human embryonic stem cells; NPC, neural progenitor cells; PDGFR, platelet-derived growth factor receptor; Gd, Gadolini
Keywords: سد خونی مغزی; BSA, bovine serum albumin; BBB, blood–brain barrier; CD, circular dichroism; CNS, central nervous system; CSNPs, core-shell nanoparticles; DLS, dynamic light scattering; FL, fluorescence spectroscopy; HPLC-MS, high performance liquid chromatography-mass s
Keywords: سد خونی مغزی; 4EPS, 4-ethylphenylsulfate; 5-HT, 5-hydroxytryptamine; AA, acetic acid; ANS, autonomic nervous system; ASD, autism spectrum disorder; BBB, blood–brain barrier; CHD8, chromodomain helicase DNA-binding protein 8; CNS, central nervous system; CRH, corticotro
Keywords: سد خونی مغزی; Trp, Tryptophan; 5-HTP, 5-hydroxytryptophan; 5-HT, serotonin; Kyn, kynurenine; BBB, blood–brain barrier; TDO, tryptophan 2,3-dioxygenase; IDO, indoleamine 2,3-dioxygenase; MacCVI, MacArthur Community Violence Instrument; LSARS, Lethality of Suicide Attemp
Keywords: سد خونی مغزی; α-SMA, Alpha smooth muscle actin; AD, Alzheimer's disease; AJ, Adherent junction; BBB, Blood–brain barrier; BECs, Brain endothelial cells; CCL2,-5, Chemokines (C-C motif) ligand 2, -5; CCM, Cerebral cavernous malformation; CXCL8,-10, Chemokines (C-X-C mot
Keywords: سد خونی مغزی; ALIX, ALG-2 interacting protein X; ATPase, adenosine triphosphatase; BBB, blood–brain barrier; CCK-8, cell counting kit-8; CD, cluster of differentiation; DIL, 1,1′-dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate; DNA, deoxyribonucleic acid;
Keywords: سد خونی مغزی; BBB, blood–brain barrier; CTLs, cytotoxic T lymphocytes; HPLC, high-performance liquid chromatography; LAT1, l-type amino acid transporter; MCF-7, human breast adenocarcinoma cell line; MCTs, monocarboxylate transporters; NK cells, natural killer cells; O
Keywords: سد خونی مغزی; ANOVA, analysis of variance; AP-1, activator protein-1; BBB, blood–brain barrier; COX-2, cicloossigenasi-2; DMSO, dimethyl sulfoxide; ELISA, enzyme-linked immunosorbent assay; IL-1β, interleukin-1β; IL-6, interleukin-6; MAPK, mitogen-activated protein kin
Keywords: سد خونی مغزی; AchE, Acetylcholinesterase; BuChE, Butyrylcholinesterase; AD, Alzheimer’s disease; Aβ, β-Amyloid; CAS, Catalytic anionic site; PAS, Peripheral anionic site; BBB, Blood–brain barrier; AβOs, Soluble Aβ oligomers; CNS, Central nervous system; NFTS, Neurofibr
Keywords: سد خونی مغزی; Preterm birth; White matter injury; Therapeutic strategies; Oligodendrocyte; Microglia; AstrogliosisA1R, adenosine 1 receptor; BBB, blood–brain barrier; BMP4, bone morphogenetic protein; CNS, central nervous system; cPVL, cystic periventricular leukomalac
Keywords: سد خونی مغزی; Ang1, angiopoietin 1; BBB, blood–brain barrier; CAA, cerebral amyloid angiopathy; CNS, central nervous system; CO, carbon monoxide; DAMPs, danger-associated molecular patterns; DC, dendritic cell; DCX, doublecortin; EP, ethyl pyruvate; GA, glycyrrhizic ac
Keywords: سد خونی مغزی; AD, Alzheimer’s disease; AChE, acetylcholinesterase; BuChE, butyrylcholinesterase; Aβ, β-amyloid peptide; BBB, blood–brain barrier; ACh, acetylcholine; MTDL, multitarget-directed ligand; EeAChE, electric eel AChE; HuAChE, human erythrocyte AChE; CAS, cata
Keywords: سد خونی مغزی; Streptozotocin; Rat dementia model; Thalidomide; Etanercept; InfliximabaCSF, artificial cerebrospinal fluid; AD, Alzheimer's disease; Aβ, amyloid beta; BBB, blood–brain barrier; CNS, central nervous system; DAB, diaminobenzidine; H&E, hematoxylin and eosi
Keywords: سد خونی مغزی; MS, multiple sclerosis; BBB, blood–brain barrier; RRMS, relapsing–remitting; PPMS, primary progressive; SPMS, secondary progressive; PRMS, progressive-relapsing; CIS, clinically isolated syndrome; CSF, cerebrospinal fluid; MMP-9, matrix metallopeptidase 9
Keywords: سد خونی مغزی; A, atropine; AChE, acetylcholinesterase; BBB, blood–brain barrier; b.w., body weight; CNS, central nervous system; FOB, functional observational battery; HPLC, high pressure liquid chromatography; i.m., intramuscularly; n, number of surviving animals; PC,
Keywords: سد خونی مغزی; BBB, blood–brain barrier; CSPGs, chondrotin sulfate proteoglycans; CTGF, connective tissue growth factor; DMEM, Dulbecco׳s modified Eagle׳s medium; ECMs, extracellular matrix proteins; EGF, epidermal growth factor; FBS, Fetal bovine serum; P/S, Penicillin
Keywords: سد خونی مغزی; BBB, blood–brain barrier; ICAM-1, intercellular adhesion molecule 1; IL1-β, interleukin 1β; miRNA, microRNA; mTOR, mammalian target of rapamycin; MTS, mesial temporal sclerosis; SE, status epilepticus; TGF-β, transforming growth factor β; TLE, temporal lo
Keywords: سد خونی مغزی; AJs, adherent junctions; ANOVA, analysis of variance; APC, activated protein C; BBB, blood–brain barrier; EBI, early brain injury; ELISA, enzyme-linked immunosorbent assay; MRI, magnetic resonance imaging; PAR-1, protease-activated receptor-1; PBS, phosph
Keywords: سد خونی مغزی; BBB, blood–brain barrier; EB, Evans-blue; PET, positron emission tomography; SPECT, single photon emission computerized tomography; MRI, magnetic resonance imaging; DCE, dynamic contrast enhanced; SNR, signal to noise ratio; Gd, gadoliniumBlood–brain barr
Keywords: سد خونی مغزی; AD, Alzheimer's disease; ApoD, apolipoprotein D; BBB, blood–brain barrier; BCSFB, blood–CSF barrier; BCNSB, blood–CNS barrier; CHI3L1, chitinase-3-like protein 1; CIS, clinical isolated syndrome; CNS, central nervous system; CP, choroid plexus; CSF, cereb
Keywords: سد خونی مغزی; AMT, adsorptive-mediated transcytosis; BBB, blood–brain barrier; BMEC, brain-microvascular endothelial cell; DMAB, didodecyldimethylammonium bromide; FA, folic acid; FA/PLGA, folic acid-grafted poly(lactide-co-glycolide); FR, folate receptor; GBM, gliobla
Keywords: سد خونی مغزی; Ang, angiopoietin; BBB, blood–brain barrier; CD, cluster of differentiation; DAMP, danger associated molecular pattern molecule; HMGB1, high morbidity group box 1; HO, heme oxygenase; ICAM-1, intercellular adhesion molecule-1; ICH, intracerebral hemorrhag
Keywords: سد خونی مغزی; ABC, ATP Binding Cassette; ALK, activin receptor-like kinase; BBB, blood–brain barrier; BCRP, Breast Cancer Resistance Protein; CNS, central nervous system; GSH, glutathione; GSSG, glutathione disulfide; JAM, junctional adhesion molecule; MAGUK, membrane-
Keywords: سد خونی مغزی; AAV, adeno-associated viruses; AGAT, arginine:glycine amidinotransferase; BBB, blood–brain barrier; CNS, central nervous system; Cr, creatine; DAPI, 4′,6-diamidino-2-phenylindole; EGFP, enhanced green fluorescent protein; GAA, guanidinoacetate; GABAAR, GA
Keywords: سد خونی مغزی; WGJe, White grape juice extract; EAE, Experimental autoimmune encephalomyelitis; MS, Multiple sclerosis; CNS, Central nervous system; BBB, Blood–brain barrier; ROS, Reactive oxygen species; H&E, Hematoxylin/eosin; LFB, Luxol Fast Blue; PARP-1, Poly (ADP-r
Keywords: سد خونی مغزی; APC, antigen presenting cell; BBB, blood–brain barrier; CCR, CC chemokine receptor; CIS, clinical isolated syndrome; CNPase, 2′,3′-cyclic-nucleotide 3′-phosphodiesterase; CNS, central nervous system; CNTF, ciliary neurotrophic factor; CSF, cerebrospinal f
Keywords: سد خونی مغزی; HIE, hypoxic–ischemic encephalopathy; BBB, blood‐brain barrier; CSF, cerebral spinal fluid; VEGF, vascular endothelial growth factor; MMP, matrix metalloproteinase; LPS, lipopolysaccharideNeurovascular unit; Blood brain barrier; Hypoxia–ischemia; Hypother
Keywords: سد خونی مغزی; AD, Alzheimer's disease; Aβ, amyloid β peptide; Aβ42, Aβ1-42; Aβ40, Aβ1-40; APP, Aβ precursor protein; BBB, blood–brain barrier; catabody, catalytic antibody; CDR, complementarity determining region; CAA, cerebral amyloid angiopathy; CHAPS, 3-[(3-cholamid
Keywords: سد خونی مغزی; α-Syn, alpha-synuclein; Aβ, amyloid-beta protein; BBB, blood–brain barrier; CNS, central nervous system; CSF, cerebrospinal fluid; DA, dopaminergic; ICV, intracerebroventricular; LBs, Lewy bodies; LPS, lipopolysaccharide; LRP-1, low-density lipoprotein re
Keywords: سد خونی مغزی; ASPA, aspartoacylase; BBB, blood–brain barrier; CD, Canavan disease; CNS, central nervous system; ERT, enzyme replacement therapy; GFAP, glial fibrillary acidic protein; IBA, ionized calcium binding adaptor protein-1; NAA, N-acetyl-l-aspartate; NECA, 1-(6
Keywords: سد خونی مغزی; Alzheimer's disease; 3xTg-AD; APP/PS1; Blood–brain barrier integrity; In situ brain perfusion; Brain vascular volumeAPP, amyloid precursor protein; AD, Alzheimer's disease; BBB, blood–brain barrier; Vvasc, brain vascular volume; Clup, brain uptake clearan
Keywords: سد خونی مغزی; AK, amygdala kindling; BBB, blood–brain barrier; FBS, fetal bovine serum; GFAP, glial fibrillary acidic protein; HS, hippocampal sclerosis; IL, interleukin; IL-1ra, IL-1 receptor antagonist; MCP, monocyte chemotactic protein-1; MIP, macrophage inflammator
Keywords: سد خونی مغزی; Leptin; Circadian rhythm; Sleep fragmentation; Sleep duration; Obstructive sleep apnea; Continuous positive airway pressureAHI, apnea–hypopnea index; BBB, blood–brain barrier; BMI, body mass index; CNS, central nervous system; CPAP, continuous positive ai
Keywords: سد خونی مغزی; Leptin; Leptin receptor; Leptin receptor modulators; Agonists; Antagonists; Leptin-related diseasesObR, leptin receptor; G-CSF, Granulocyte Colony-Stimulating Factor; BBB, blood–brain barrier; ER-α, estrogen receptor alpha; IGF-I, insulin-like growth fact
Keywords: سد خونی مغزی; BBB, blood–brain barrier; TJ, tight junctions; HIF-1α, hypoxia-inducible factor-1α; VEGF, vascular endothelial growth factorIsoflurane; Blood–brain barrier; Hypoxia inducible factor-1α; Occludin; VEGF; TGF-β3
Keywords: سد خونی مغزی; 5-LO, 5-lipoxygenase; BBB, blood–brain barrier; EB, Evan's blue; fEPSP, field excitatory post-synaptic potential; FLAP, 5-lipoxygenase activating protein; FPI, fluid percussion injury; Gd, gadolinium-diethylenetriamine pentaacetic acid; LTP, long-term pot
Keywords: سد خونی مغزی; 3HBD, R-3HB dehydrogenase; AT, acetoacetyl thiolase; AcAc, acetoacetate; ATP, adenosine triphosphate; BBB, blood–brain barrier; CBF, cerebral blood flow; CMR, cerebral metabolic rate; CoA, coenzyme A; CPT1, carnithine pamitoyl transporter 1; FDG, fluorode
Keywords: سد خونی مغزی; ABCA1, ATP-binding cassette transporter A1; ACAT, acyl-CoA:cholesterol acyltransferase; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; APOE, apolipoprotein E; BBB, blood–brain barrier; CEs, cholesterol esters; CJD, Creutzfeldt–Jakob disease;
Keywords: سد خونی مغزی; AIDS, acquired immunodeficiency syndrome; BBB, blood–brain barrier; BCA, bicinchoninic acid; CB, cacao butter; DSPE-PEG(2000)-CA, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)-2000]; DYN, Dynasan 114; ELISA, enzyme-linked
Keywords: سد خونی مغزی; Atorvastatin (PubChem CID: 60823); Lovastatin (PubChem CID: 53232); Simvastatin (PubChem CID: 54454)APC, antigen-presenting cell; ARR, annualized rate of relapse; BBB, blood–brain barrier; CNS, central nervous system; DC, dendritic cell; DMT, disease-modi
Keywords: سد خونی مغزی; PTX, paclitaxel; SLN, solid lipid nanoparticles; BA, behenic acid; ST, stearylamine; GCS, glycol chitosan; BBB, blood–brain barrier; GBM, glioblastoma multiforme; CNS, central nervous system; NP, nanoparticles; CBSA, cationic bovine serum albumin; NHEJ, n
Keywords: سد خونی مغزی; ACPPs, activable CPPs; AE, active enediyne chromophore; alpha-GC, alpha-galactosylceramide; AoA, aminooxyacetic acid; APC, antigen presenting cell; ASCs, adipose tissue-derived stem cells; BBB, blood–brain barrier; β-CyD, β-cyclodextrin; β-gal, β-galactos
Keywords: سد خونی مغزی; Aβ, amyloid β; AD, Alzheimer's disease; AMPA, α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid; APP, amyloid precursor protein; Atox 1, human antioxidant protein 1; Atx1, antioxidant protein 1; BBB, blood–brain barrier; BCB, blood–cerebrospinal fluid
Keywords: سد خونی مغزی; HDL, high-density lipoprotein; LDL, low-density lipoprotein; BBB, blood–brain barrier; apo E, apolipoprotein E; DPBS, Dulbecco׳s phosphate buffered saline; FCS, fetal calf serum; DMEM, Dulbecco׳s modified Eagle medium; BSA, bovine serum albumin; TLC, thin
Changes in endothelial cell proliferation and vascular permeability after systemic lipopolysaccharide administration in the subfornical organ
Keywords: سد خونی مغزی; BBB, blood–brain barrier; BrdU, 5-bromo-2′-deoxyuridine; CVO, circumventricular organ; Dex70k, Dextran 70,000; DSHB, Developmental Studies of Hybridoma Bank; FITC, fluorescein isothiocyanate; LPS, lipopolysaccharide; PB, phosphate buffer; PBS, phosphate-b
In vivo imaging in autoimmune diseases in the central nervous system
Keywords: سد خونی مغزی; Antigen presentation; Autoimmunity; Central nervous system; Intravital imaging; T cellsAPCs, antigen presenting cells; BBB, blood–brain barrier; CFP, cyan fluorescent protein; CFSE, 5-(and-6)-carboxyfluorescein diacetate succinimidyl ester; CMTMR, 5-(and-
Pyrazole antagonists of the CB1 receptor with reduced brain penetration
Keywords: سد خونی مغزی; BBB, blood–brain barrier; BOP, benzotriazol-1-yl-oxytris(dimethylamino)phosphonium hexafluorophosphate; CB, cannabinoid receptors; CB1, cannabinoid receptor 1; CB2, cannabinoid receptor 2; CHO-K1, Chinese hamster ovary cells; CMA 80, 80% chloroform, 18% m
Bone marrow stromal cells inhibits HMGB1-mediated inflammation after stroke in type 2 diabetic rats
Keywords: سد خونی مغزی; BBB, blood–brain barrier; BMSCs, bone marrow stromal cells; DM, diabetes mellitus; HMGB1, high-mobility group box 1; MCAo, middle cerebral artery occlusion; mNSS, modified neurological severity score; OGD, oxygen glucose deprivation; PBS, phosphate-buffer