Reconstruction and exploration of virtual middle-ear models derived from micro-CT datasets

BackgroundMiddle-ear anatomy is integrally linked to both its normal function and its response to disease processes. Micro-CT imaging provides an opportunity to capture high-resolution anatomical data in a relatively quick and non-destructive manner. However, to optimally extract functionally relevant details, an intuitive means of reconstructing and interacting with these data is needed.Materials and methodsA micro-CT scanner was used to obtain high-resolution scans of freshly explanted human temporal bones. An advanced volume renderer was adapted to enable real-time reconstruction, display, and manipulation of these volumetric datasets. A custom-designed user interface provided for semi-automated threshold segmentation. A 6-degrees-of-freedom navigation device was designed and fabricated to enable exploration of the 3D space in a manner intuitive to those comfortable with the use of a surgical microscope. Standard haptic devices were also incorporated to assist in navigation and exploration.ResultsOur visualization workstation could be adapted to allow for the effective exploration of middle-ear micro-CT datasets. Functionally significant anatomical details could be recognized and objective data could be extracted.ConclusionsWe have developed an intuitive, rapid, and effective means of exploring otological micro-CT datasets. This system may provide a foundation for additional work based on middle-ear anatomical data.