کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4356054 | 1615657 | 2008 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Intraneural stimulation for auditory prosthesis: Modiolar trunk and intracranial stimulation sites
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کلمات کلیدی
CATICCUEAeABR - EABRIntracranial - داخل جمجمهAuditory nerve - عصب شنواییCochlear nerve - عصب کچلرCharacteristic Frequency - فرکانس مشخصهCentral Nucleus of the Inferior Colliculus - هسته مرکزی کولیکولوس پایینElectrically-evoked auditory brainstem response - پاسخ مغزی شنوایی شنوایی الکتریکیCochlear implant - کاشت حلزونیInferior colliculus - کولیکولوس پایین
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
سیستم های حسی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
We have demonstrated recently in an animal model that stimulation with a penetrating auditory nerve electrode array is a feasible means of activating the ascending auditory pathway for auditory prosthesis. Compared to a conventional intrascalar cochlear implant, intraneural stimulation provides access to fibers serving a broader frequency range, activation of more tonotopically restricted fiber populations, lower thresholds, and reduced interference between simultaneously stimulated channels. The spread of excitation by a single intraneural electrode is broader than that by an acoustic tone but narrower than that by a cochlear-implant electrode. In the present study, we compare in an animal model two sites of intraneural stimulation: the modiolar trunk of the nerve accessed using a transcochlear approach and the intracranial portion of the nerve accessed using a posterior fossa approach. The two stimulation sites offer very similar thresholds, spread of activation, and dynamic ranges. The intracranial site differed in that there was greater between-animal variation in tonotopic patterns. We discuss the implications of these results for possible improvements in hearing prosthesis for human subjects.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Hearing Research - Volume 242, Issues 1â2, August 2008, Pages 52-63
Journal: Hearing Research - Volume 242, Issues 1â2, August 2008, Pages 52-63
نویسندگان
John C. Middlebrooks, Russell L. Snyder,