کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4368273 | 1616661 | 2011 | 4 صفحه PDF | دانلود رایگان |
A total of 81 Salmonella isolates from retail meats and seafood in Hebei province, China, were assayed for the presence of and horizontal transfer of class 1 integrons. By the PCR screening for the integrons, class 1 integron was detected from strains in serotypes of Derby, Indiana, London and Choleraesuis, which were isolated from pork, chicken or seafood; however, two isolates contained the empty integron that lacked the resistance cassette, a potential hotspot for development of the multidrug resistance. In contrast, two other isolates had the antibiotic resistance gene cassettes within the class 1 integron, which were dfrA1-aadA1 and aadB-cmlA, respectively. The conjugation experiments demonstrated the plasmid-mediated transfer of the class 1 integrons. Furthermore, each of the integrons was transmitted to Streptococcus mutans via natural gene transformation. These findings suggest the possible transfer of class 1 integrons from foodborne pathogens to human residential bacteria via horizontal gene transfer.
► Salmonella isolates were assayed for the horizontal transfer of class 1integrons.
► Two isolates had the gene cassettes within the class 1 integron.
► Each of the integrons was transmitted to Streptococcus mutans by transformation.
► Results show the possibility for transfer of class 1 integrons through food chains.
Journal: International Journal of Food Microbiology - Volume 149, Issue 3, 3 October 2011, Pages 274–277