کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4369735 1616754 2007 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Characterization of Lactobacillus plantarum PH04, a potential probiotic bacterium with cholesterol-lowering effects
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش تغذیه
پیش نمایش صفحه اول مقاله
Characterization of Lactobacillus plantarum PH04, a potential probiotic bacterium with cholesterol-lowering effects
چکیده انگلیسی

The bacterium Lactobacillus plantarum PH04 was isolated from infant feces and tested positive for bile/acid tolerance and bile salt hydrolase activity. It was evaluated as a potential probiotic with cholesterol-lowering effect. Bile salt hydrolase activity was nine times greater in stationary phase than in exponential phase cells and increased when the cells were exposed to conjugated bile salts. L. plantarum PH04 was resistant to seven of nine antibiotics tested and did not produce β-glucuronidase. L. plantarum PH04 was fed to hypercholesterolemic mice at numbers of 107 CFU per mouse per day for 14 days. Compared with a control group, the serum cholesterol and triglycerides were respectively 7 and 10% lower in the group fed L. plantarum PH04, and fecal lactic acid bacteria increased while no any significant differences (P < 0.05) in body weight, visceral weigh index or bacteria translocation between two groups were observed. The results indicated that L. plantarum PH04 might be effective as a probiotic with cholesterol-lowering activities.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Food Microbiology - Volume 113, Issue 3, 15 February 2007, Pages 358–361
نویسندگان
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