Single and Combined Cytotoxicity Research of Propiconazole and Nano-zinc Oxide on the NIH/3T3 Cell

This study chose the propiconazole and nano-zinc oxide of different particle size as the study object. The single and combined toxicity on the mouse embryonic fibroblast cell (NIH/3T3) was researched. The results showed that the cell growth was inhibited by propiconazole and nano zinc oxide of different concentrations, and it presents a dose- response relationship. When the two substances are combined, the combined of nanoscale particles produces the antagonism effect, and the combined of micron scale particles could generate synergy effect.