Effects of microcystin-LR exposure on matrix metalloproteinase-2/-9 expression and cancer cell migration

► Microcystin-LR exposure stimulates cancer cellular migration. ► Chronic microcystin-LR exposure, even at 1 nM, increases metalloproteinases expression. ► Microcystin-LR has time/dose-dependent effects on cancer cell migration and metalloproteinases-2/-9 expression.