کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4421542 1308515 2009 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Molecular connectivity indices for predicting bioactivities of substituted nitrobenzene and aniline compounds
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم محیط زیست شیمی زیست محیطی
پیش نمایش صفحه اول مقاله
Molecular connectivity indices for predicting bioactivities of substituted nitrobenzene and aniline compounds
چکیده انگلیسی

Bioconcentration and toxicity of 22 substituted nitrobenzene and aniline compounds to aquatic organisms were assessed with quantitative structure–activity relationship (QSAR). Acute toxicities of aquatic organisms, including daphnia (Daphnia pulex) and carp (Cyprinus carpio), to 22 chemicals have been determined in our previous work. In this study, the bioconcentration factors (BCFs) for carp were further investigated. By the use of multiple-regression analyses, the molecular connectivity indices (MCIs) can describe both acute toxicity and bioconcentration for the test organisms. Applicable QSAR model (0.856

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Ecotoxicology and Environmental Safety - Volume 72, Issue 7, October 2009, Pages 1942–1949
نویسندگان
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