کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4421875 | 1308524 | 2008 | 9 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Testicular functions and serum titers of LH and testosterone in methyl parathion-fed roseringed parakeets Testicular functions and serum titers of LH and testosterone in methyl parathion-fed roseringed parakeets](/preview/png/4421875.png)
Adult male roseringed parakeets were fed concentrations (0, 10 or 20 μg/100 g body wt./day) of methyl parathion (MP) for 5 or 10 days. There were four sampling periods for each treatment group. The first two sampling periods were after 5 or 10 days of daily dosing. In two other sampling periods, birds were given daily doses for 10 days, and sampling occurred at 5 or 10 days after the end of treatment. A significant dose- and duration-dependent reduction in the paired testicular weight, seminiferous tubular diameters, the number of tubules with healthy germ cells, plasma acetylcholinesterase (AChE) activity and plasma levels of luteinizing hormone (LH) and testosterone occurred in MP-fed birds. The inhibitory influences of MP persisted till day-5 and followed by recovery from the gonado-suppressive effects of MP at day-10 after the end of last treatment for 10 days. These findings provide the first experimental evidence that MP-induced testicular dysfunctions in parakeets possibly results from an impaired activity of hypophysial-gonadal axis. Moreover, it is evident that the organophosphorous (OP)-induced changes in the avian testes are reversible.
Journal: Ecotoxicology and Environmental Safety - Volume 71, Issue 1, September 2008, Pages 236–244