کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4421902 1308525 2010 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Cerium caused life span shortening and oxidative stress resistance in Drosophila melanogaster
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم محیط زیست شیمی زیست محیطی
پیش نمایش صفحه اول مقاله
Cerium caused life span shortening and oxidative stress resistance in Drosophila melanogaster
چکیده انگلیسی

To investigate the effects of the rare earth element cerium (Ce) on the life span and biomarkers of oxidative stress in the fruit fly (Drosophila melanogaster). Fruit flies were fed on media with different dose of ceric sulfate (1, 4, 16, 64, 256, 1024 mg/L, corresponding to cerium concentrations of 0.45, 1.65, 6.91, 26.3, 104, and 429 μg/g culture medium). Mean life span, maximum life span, and fertility were calculated. There was a significant decrease in mean life span and maximum life span with increasing doses of cerium. At some concentrations, there was a decrease in reproductive output, especially concentrations >6.91 μg/g. We also measured superoxide dismutase (SOD) activity, catalase (CAT) activity, and lipid peroxidation product levels (malondialdehyde (MDA) content). Cerium caused a significant increase in MDA content and decrease in SOD and CAT activities at concentrations >6.91 μg/g. These results suggest that cerium may result in oxidative toxicity to D. melanogaster.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Ecotoxicology and Environmental Safety - Volume 73, Issue 1, January 2010, Pages 89–93
نویسندگان
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