کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4425756 1309112 2010 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Endocrine modulation, inhibition of ovarian development and hepatic alterations in rainbow trout exposed to polluted river water
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم محیط زیست شیمی زیست محیطی
پیش نمایش صفحه اول مقاله
Endocrine modulation, inhibition of ovarian development and hepatic alterations in rainbow trout exposed to polluted river water
چکیده انگلیسی

Under laboratory conditions, female rainbow trout were exposed to graded concentrations of water from the River Lambro, a polluted tributary of the River Po, and to the effluent of a large wastewater treatment plant which flows into the River Lambro. In field exposures, trout were held in cages in the River Po upstream and downstream from the confluence of the River Lambro. After 10-day (laboratory) and 30-day (laboratory and field) exposures, trout were examined for several chemical, biochemical and histological endpoints. The results indicated that exposure to complex mixtures of chemicals, including estrogen receptor agonists, aryl-hydrocarbon receptor agonists, and probably antiandrogens, had occurred. Exposure altered the plasma levels of 17β-estradiol and testosterone, and some treatments also enhanced the activity of hepatic ethoxyresorufin O-deethylase. Gonadal histology showed varying levels of degenerative processes characterised by oocyte atresia, haemorrhages, melano-macrophage centres (MMCs), and oogonia proliferation. Liver histology showed less severe effects.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Environmental Pollution - Volume 158, Issue 12, December 2010, Pages 3675–3683
نویسندگان
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