کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4426540 | 1309128 | 2009 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Adsorption and transformation of selected human-used macrolide antibacterial agents with iron(III) and manganese(IV) oxides Adsorption and transformation of selected human-used macrolide antibacterial agents with iron(III) and manganese(IV) oxides](/preview/png/4426540.png)
The adsorption/transformation of two members (clarithromycin and roxithromycin) of the macrolide (ML) antibacterial agents on the surface of three environmental subsurface sorbents (clay, iron(III) and manganese(IV) oxy-hydroxides) was investigated. The adsorption fitted well to the Freundlich model with a high sorption capacity. Adsorption probably occurred through a surface complexation mechanism and was accompanied by slow degradation of the selected MLs. Transformation proceeded through two parallel pathways: a major pathway was the hydrolysis of the cladinose sugar, and to a lesser extent the hydrolysis of the lactone ring. A minor pathway was the N-dealkylation of the amino sugar. This study indicates that Fe(III) and Mn(IV) oxy-hydroxides in aquatic sediments may play an important role in the natural attenuation of MLs. Such an attenuation route yields a range of intermediates that might retain some of their biological activity.
Journal: Environmental Pollution - Volume 157, Issue 4, April 2009, Pages 1317–1322