کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4426671 1309133 2009 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Genotoxicity of water from the Songhua River, China, in 1994–1995 and 2002–2003: Potential risks for human health
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم محیط زیست شیمی زیست محیطی
پیش نمایش صفحه اول مقاله
Genotoxicity of water from the Songhua River, China, in 1994–1995 and 2002–2003: Potential risks for human health
چکیده انگلیسی

A previous study showed that the cancer mortalities are higher for residents who lived nearby the Songhua River heavily polluted by organic contamination. It is important to determine its risk of carcinogenic potential. Short-term genotoxic bio-assays using Salmonella, Sister Chromatid Exchange (SCE), and Micronuclei (MN) assays were employed to examine the genotoxic activity of ether extracts of water samples taken from the Songhua River. The results of the Salmonella bioassay indicated that there were indirect frame-shift mutagens in the water samples. A dose–response relationship for the SCE and MN assays was obtained. These results showed that organic extracts of water samples have genotoxic activity and the risk of carcinogenic potential to human health. The mutagenesis of water samples had changed compared to the results in 1994–1995. An increasing trend of risk of carcinogenic potential in the Songhua River after ten years should be noted and needs to be studied further.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Environmental Pollution - Volume 157, Issue 2, February 2009, Pages 357–364
نویسندگان
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