کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4496036 | 1623834 | 2015 | 9 صفحه PDF | دانلود رایگان |
• We derived a conserved quantity from a basic model of viral infection.
• We gave a feasible biological interpretation for the conserved quantity.
• We calculated the conserved quantity based on cell culture viral experimental data.
Conservation laws are among the most important properties of a physical system, but are not commonplace in biology. We derived a conservation law from the basic model for viral infections which consists in a small set of ordinary differential equations. We challenged the conservation law experimentally for the case of a virus infection in a cell culture. We found that the derived, conserved quantity remained almost constant throughout the infection period, implying that the derived conservation law holds in this biological system. We also suggest a potential use for the conservation law in evaluating the accuracy of experimental measurements.
Journal: Journal of Theoretical Biology - Volume 376, 7 July 2015, Pages 39–47