کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4497255 1318926 2010 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A folding “framework structure” of Tetrahymena group I intron
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم کشاورزی و بیولوژیک (عمومی)
پیش نمایش صفحه اول مقاله
A folding “framework structure” of Tetrahymena group I intron
چکیده انگلیسی

We have published the dynamic extended folding (DEF) method, which is a RNA secondary structure prediction approach—to simulate the in vivo RNA co-transcriptional folding process. In order to verify the reliability of the method, we selected the X-ray-determined Tetrahymena group I intron as a sample to construct the framework of its folding secondary structure. Our prediction coincides well with the secondary structure predicted by T.R. Cech and the X-ray diffraction crystal structure determined by Lehnert V. Our results show that the DEF framework structure of Tetrahymena group I intron reflects its function sites in a concise and straightforward manner, and the scope of the simulation was expanded.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Theoretical Biology - Volume 267, Issue 4, 21 December 2010, Pages 495–501
نویسندگان
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