کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4497685 1318946 2009 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
TN curve: A novel 3D graphical representation of DNA sequence based on trinucleotides and its applications
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم کشاورزی و بیولوژیک (عمومی)
پیش نمایش صفحه اول مقاله
TN curve: A novel 3D graphical representation of DNA sequence based on trinucleotides and its applications
چکیده انگلیسی

In this paper, a novel 3D graphical representation of DNA sequence based on trinucleotides is proposed. This representation allows direct inspection of composition as well as distribution of trinucleotides in DNA sequence for the first time and avoids loss of information, from which one can obtain more information. Based on this novel model, six numerical descriptors of DNA sequence are deduced without complicated calculations, and the applications in similarities/dissimilarities analysis of coding sequences and conserved genes discrimination illustrate their utilities. In addition, two simple methods for similarities/dissimilarities analysis of coding sequences among different species are exploited by using two vectors composed of 64 and six components, respectively, which can provide convenient sequence alignment tools for both computational scientists and molecular biologists.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Theoretical Biology - Volume 261, Issue 3, 7 December 2009, Pages 459–468
نویسندگان
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