کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4498196 | 1318969 | 2008 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The transition from differential equations to Boolean networks: A case study in simplifying a regulatory network model
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم کشاورزی و بیولوژیک (عمومی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: The transition from differential equations to Boolean networks: A case study in simplifying a regulatory network model The transition from differential equations to Boolean networks: A case study in simplifying a regulatory network model](/preview/png/4498196.png)
چکیده انگلیسی
Methods for modeling cellular regulatory networks as diverse as differential equations and Boolean networks co-exist, however, without much closer correspondence to each other. With the example system of the fission yeast cell cycle control network, we here discuss these two approaches with respect to each other. We find that a Boolean network model can be formulated as a specific coarse-grained limit of the more detailed differential equations model for this system. This demonstrates the mathematical foundation on which Boolean networks can be applied to biological regulatory networks in a controlled way.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Theoretical Biology - Volume 255, Issue 3, 7 December 2008, Pages 269–277
Journal: Journal of Theoretical Biology - Volume 255, Issue 3, 7 December 2008, Pages 269–277
نویسندگان
Maria Davidich, Stefan Bornholdt,