کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4512667 1624833 2015 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Isolation of lupeol from white oak leaves and its anti-inflammatory activity
ترجمه فارسی عنوان
جداسازی لوپئول از برگ های بلوط سفید و فعالیت ضد التهابی آن
کلمات کلیدی
لوپه، فعالیت ضد سیکلوکوکسیژناز، پاکسازی، کروماتوگرافی
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم زراعت و اصلاح نباتات
چکیده انگلیسی


• Lupeol was found only in Quercus obtusata species.
• A simple method to extract and purify lupeol from Quercus obtusata was developed.
• Antiinflammatory activity of Quercus obtusata could be related with inhibition of COX-2.

Lupeol [lup-20(29)-en-2-ol] is found mainly on the surface of plant barks, stems, leaves and fruits waxes. This research explored oaks leaves of several species (Quercus resinosa, Q. grisea, Q. laeta and Q. obtusata) as potential source of lupeol. It was extracted from Quercus leaves by maceration with CHCl3 at 35 °C, followed by a purification in silica column (normal phase), and using as mobile phase hexane (100%), hexane:ethyl acetate (90:10) and hexane:ethyl acetate (80:20). Lupeol in oak leaves was identified by 13C NMR and quantified by GC–MS. Quercus obtusata leaves were an abundant source of lupeol (173.59 μg/g of sample). Anti-cyclooxygenase activity has been used for determining bioactivity of lupeol in this research.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Industrial Crops and Products - Volume 77, 23 December 2015, Pages 827–832
نویسندگان
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