کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4511936 1624815 2017 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Bioactive metabolites involved in the antioxidant, anticancer and anticalpain activities of Ficus carica L., Ceratonia siliqua L. and Quercus ilex L. extracts
ترجمه فارسی عنوان
متابولیت های فعال زیست فعال در فعالیت های آنتی اکسیدان، ضد سرطان و ضد عفونی Ficus carica L.، Ceratonia siliqua L. و عصاره Quercus Ilex L.
کلمات کلیدی
فنولیک؛ پروفیل کاروتنوئید؛ فعالیت های آنتیاکسیدانی؛ فعالیت کالپین؛ اثر ضد تکثیری
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم زراعت و اصلاح نباتات
چکیده انگلیسی


• High phenolics, flavonoids and ortho-diphenols contents were found in Quercus ilex..
• Quercus ilex and Ceratonia siliqua were very effective in scavenging free radicals.
• Ceratonia siliqua and Quercus ilex inhibited strongly lucigenin chemiluminescence.
• Figs, carobs and acorns decreased calpain activity.
• Quercus ilex and Ceratonia siliqua exerted an antiproliferative effect.

Ficus carica L., Ceratonia siliqua L. and Quercus ilex L. are natural products that are used as an advantageous rich source of bioactive compounds of high economic value because of its use in cosmetic, pharmaceutical and agriculture industries. These crops were studied for its phytochemical contents and were investigated for antioxidant activities and its effects on reactive oxygen species (ROS) production, calpain activity and antiproliferative effects. Results showed that extremely high total contents of phenolics, flavonoids and ortho-diphenols were detected in Quercus ilex, while proanthocyanidin level was higher in Ficus carica. Ceratonia siliqua pods showed more carotenoids and had the highest lightness value (L*). Quercus ilex and Ceratonia siliqua extracts were very effective in scavenging free radicals. The best hydroxyl radical scavenging activity was attributed to Quercus ilex with 80.51 ± 0.20% while nitric oxide assay showed no significant differences between extracts. Ficus carica presented a higher reducing ability with 638.23 ± 0.43 mg gallic acid equivalents/100 g, while Quercus ilex was very potent in reducing power assays. Percentages of metal chelating capacities of Quercus ilex and Ficus carica extracts were 87.87 ± 0.34 and 73.17 ± 0.16%, respectively. These two samples were also able to scavenge hydrogen peroxide efficiently. At 250 μg/mL, Quercus ilex presented the best xanthine oxidase inhibition, 89.81 ± 0.36%. Ceratonia siliqua and Quercus ilex extracts presented the best capacities of ROS inhibition and reduced cell viability in a concentration dependent manner. All samples decreased calpain activity. These extracts could be further exploited as a source of natural products with antioxidant and anticancer effects.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Industrial Crops and Products - Volume 95, January 2017, Pages 6–17
نویسندگان
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