Alhagi maurorum: A convenient source of lupeol

Lupeol, a bioactive triterpenoid, has been isolated from the root barks of Alhagi maurorum for the first time in considerable quantity via an easy extraction and isolation process. In this study, a new and versatile LC–MS method has also been developed by optimizing various parameters for the rapid determination of lupeol in plant extract. The anti-inflammatory property of A. maurorum can be correlated to this compound. The superiority of A. maurorum over other plant sources of lupeol is due to its wild nature and ability to grow throughout the year. On the basis of this fact, A. maurorum can be used as a cheaper and ever available source for the lupeol.

► Isolation of a potent bioactive compound, lupeol for the first time from wild plant Alhagi maurorum.
► This is first report in which isolation of anti-inflammatory compound has been isolated from this plant.
► Lupeol has never been isolated in quantity in which it is found in A. maurorum (0.11% w/w).
► After extraction and purification it was analyzed by LC–MS method (self developed and validated for analysis of lupeol).
► Method is suitable for extraction, purification and analysis of lupeol in plant extracts.