کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4564131 1330927 2010 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Activity of water-soluble turmeric extract using hydrophilic excipients
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش تغذیه
پیش نمایش صفحه اول مقاله
Activity of water-soluble turmeric extract using hydrophilic excipients
چکیده انگلیسی

Turmeric (Curcuma longa) is extensively used in a number of ailments by the traditional medical practitioners. Traditionally turmeric is extracted with different non-edible organic solvents or supercritical fluid extraction using carbon dioxide and suffers from many drawbacks as it fails to achieve aqueous solubility, acceptable content of active principle in edible form and stability in biofluids. In the present work we report application of food-grade polyglycolized glycerides to obtain water-soluble extract of turmeric, which contains lipophilic curcuminoids in the aqueous phase. Extraction of turmeric using amphiphilic vehicles such as Gelucire 44/14, Gelucire 50/13, and PEG 6000 was able to achieve aqueous solubility. Gelucire 44/14 gives the maximum concentration of curcuminoids than extraction with Gelucire 50/13 and PEG 6000, as quantified with RP-HPLC. Turmeric extract was further screened for in vitro free radical scavenging assays, ROS scavenging ability and cell proliferation activity in cell line.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: LWT - Food Science and Technology - Volume 43, Issue 1, January 2010, Pages 59–66
نویسندگان
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