کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4970643 | 1450227 | 2017 | 16 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A computational design of a versatile microchamber for in vitro nanosecond pulsed electric fields experiments
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی کامپیوتر
سخت افزارها و معماری
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: A computational design of a versatile microchamber for in vitro nanosecond pulsed electric fields experiments A computational design of a versatile microchamber for in vitro nanosecond pulsed electric fields experiments](/preview/png/4970643.png)
چکیده انگلیسی
The emergence of nanosecond pulsed electric fields (nsPEFs) for intracellular manipulation experiments requires the use of specific miniaturized applicators. We propose the design of a versatile nsPEFs applicator, based on microwave propagating systems, suitable for in vitro exposure to undistorted 1-3Â ns pulses in single and multi-cell experiments. Further features of the proposed devices are: high efficiency, microfluidic integration, real time monitoring of the biological sample and of the pulse propagation. Generally, these features can be considered as specific requisites for nanosecond applicators, to ensure experimental repeatability and reproducibility, when propagation related phenomena cannot be considered negligible.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Integration, the VLSI Journal - Volume 58, June 2017, Pages 446-453
Journal: Integration, the VLSI Journal - Volume 58, June 2017, Pages 446-453
نویسندگان
Maura Casciola, Micaela Liberti, Agnese Denzi, Alessandra Paffi, Caterina Merla, Francesca Apollonio,