Postsynthetic modification of metal–organic framework as a highly efficient and recyclable catalyst for three-component (aldehyde–alkyne–amine) coupling reaction

A MOF-supported Cu(I) catalyst bearing N,O-chelating ligand was prepared through postsynthetic modification of IRMOF-3 and used as an efficient heterogeneous catalyst for three-component coupling reaction of aldehyde, alkyne, and amine. The catalyst exhibited both high catalytic activity and stability for the reaction and the framework of Cu(I) catalyst was mainly maintained after the catalyst was reused for four times.

Postsynthetic modification of metal–organic framework as a highly efficient and recyclable catalyst for three-component (aldehyde–alkyne–amine) coupling reaction.Figure optionsDownload as PowerPoint slideHighlights
► A Cu(I) complex was immobilized to IRMOF-3 via postsynthetic modification.
► The MOF-supported Cu(I) catalyst was used for the A3-coupling reaction.
► The Cu(I) catalyst exhibited good activity and structural stability.