Evaluation of the utility of lanthanide salts as catalysts for the per-O-acetylation of monosaccharides

The simple, commonly occurring salts across the lanthanide period were examined as O-acetylation catalysts for monosaccharides. It was found that regardless of the temperature or gegenion, these compounds in combination with Ac2O were highly efficient and effective in a per-O-acetylation catalysis transformation.

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► Simple, readily available Lanthanide salts were excellent O-acetylation catalysts.
► Monosaccharides were per-O-acetylated in excellent yield.
► Catalytic efficiency was observed even at 0.001 mol% loading.