Iridium-catalyzed aerobic oxidation of alkylarenes with excellent turnover numbers

A highly efficient catalyst system has been developed for the aerobic oxidation of alkylarenes under solvent free conditions. The combination of iridium complex, nitrogen ligand and iodobenzene was found to be crucial for catalytic activity. Excellent turnover numbers were achieved for the preparation of benzoic acids and aryl ketones. This finding may provide useful clues for improving commercially important oxidation processes.

A highly efficient catalyst system has been developed for the aerobic oxidation of alkylarenes under solvent free conditions. The combination of iridium complex, nitrogen ligand and iodobenzene was found to be crucial for catalytic activity. Excellent turnover numbers were achieved for the preparation of benzoic acids and aryl ketones.Figure optionsDownload as PowerPoint slideHighlights
► Combination of iridium complex, nitrogen ligand and iodobenzene provided an extremely active catalyst system.
► Aerobic oxidation of alkylarenes under solvent free conditions.
► Excellent turnover numbers were achieved for the preparation of benzoic acids an aryl ketones.