Palladium nanoparticles catalyzed Sonogashira reactions for the one-pot synthesis of symmetrical and unsymmetrical diarylacetylenes

• Ligand-free PdNPs catalyzed one-pot synthesis of diarylacetylenes.
• A variety of symmetrical and unsymmetrical diarylacetylenes are synthesized.
• All catalytic transformations were performed under mild reaction conditions.

A variety of symmetrical and unsymmetrical diarylacetylenes are synthesized by ligand-free palladium nanoparticles catalyzed copper-free and amine-free Sonogashira cross-coupling reactions between aryl iodides and trimethylsilylacetylene (TMSA) under mild reaction conditions.

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