کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5041744 1474156 2017 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Assessing pain in patients with chronic disorders of consciousness: Are we heading in the right direction?
ترجمه فارسی عنوان
ارزیابی درد در بیماران مبتلا به اختلالات مزمن آگاهی: آیا ما در مسیر درست قرار داریم؟
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب شناختی
چکیده انگلیسی


- Pain-motor integration damage compromises pain-related behavioral responsiveness.
- IPI variability of N2-P2 estimates the connectivity of pain-motor integration processes.
- IPI variability may be an objective measure of pain processing in DoC.

The deterioration of sensory-motor integration within the pain matrix in patients with chronic Disorders of Consciousness (DoC) is one of the principal mechanisms responsible for non-conscious pain perception. The present study aimed to assess whether the variability in the inter-peak interval (IPI) between the N2 and P2 components of laser evoked potentials (LEP) could represent an objective marker of the behavioral responsiveness to nociceptive stimulation, as measured by the Nociception Coma Scale-Revised (NCS-R), and regardless of the sensory part of pain processing. We found that only IPI variability showed a significant correlation with NCS-R score, independently of the stimulation intensity (that influences the sensory part of pain processing). It was thus concluded that IPI variability might represent an objective measure of pain processing, which may help clinicians in the development of effective pain management strategies.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Consciousness and Cognition - Volume 55, October 2017, Pages 148-155
نویسندگان
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