کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5043593 1475300 2016 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The organizing actions of adolescent gonadal steroid hormones on brain and behavioral development
ترجمه فارسی عنوان
اقدامات سازمانی هورمونهای استروئیدی گنادان نوجوان بر روی مغز و توسعه رفتاری
کلمات کلیدی
بلوغ، فرضیه فعال سازی-سازمانی، رفتار اخلاقی، رفتار اضطراب مانند، قشر استروژن، رفتار بدبینانه، دوره های حساس، رفتار جنسی، هرس سیناپتیس، تستوسترون،
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
چکیده انگلیسی


- Adolescence is a sensitive period for the effects of hormones on brain and behavior.
- Testicular hormones masculinize and defeminize social and reproductive behaviors.
- Ovarian hormones have both feminizing and defeminizing effects on female behavior.
- Gonadal steroid hormones drive many brain structural changes during adolescence.
- Adolescence may be part of a protracted postnatal steroid-sensitive period.

Adolescence is a developmental period characterized by dramatic changes in cognition, risk-taking and social behavior. Although gonadal steroid hormones are well-known mediators of these behaviors in adulthood, the role gonadal steroid hormones play in shaping the adolescent brain and behavioral development has only come to light in recent years. Here we discuss the sex-specific impact of gonadal steroid hormones on the developing adolescent brain. Indeed, the effects of gonadal steroid hormones during adolescence on brain structure and behavioral outcomes differs markedly between the sexes. Research findings suggest that adolescence, like the perinatal period, is a sensitive period for the sex-specific effects of gonadal steroid hormones on brain and behavioral development. Furthermore, evidence from studies on male sexual behavior suggests that adolescence is part of a protracted postnatal sensitive period that begins perinatally and ends following adolescence. As such, the perinatal and peripubertal periods of brain and behavioral organization likely do not represent two discrete sensitive periods, but instead are the consequence of normative developmental timing of gonadal hormone secretions in males and females.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience & Biobehavioral Reviews - Volume 70, November 2016, Pages 148-158
نویسندگان
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