کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5043752 1475299 2016 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Decision-making ability in current and past users of opiates: A meta-analysis
ترجمه فارسی عنوان
توانایی تصمیم گیری در کاربران فعلی و گذشته مواد مخدر: یک متا آنالیز
کلمات کلیدی
تصمیم سازی، شناخت، تکانشی، اپیدمی هروئین، بی حوصلگی اعتیاد،
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
چکیده انگلیسی


- Opiate users are consistently impaired on a range of different aspects of decision-making.
- Severe deficits were still present in opiate-users even after cessation of use.
- Deficits could not be accounted for by co-morbid conditions such as polydrug use and head injury.

Opiate use is associated with deficits in decision-making. However, the impact of abstinence and co-morbid factors, like head injury and poly-substance abuse, on this ability, is currently unclear. This meta-analysis aimed to assess 1) the magnitude of decision-making deficits in opiate users; 2) whether co-morbid factors moderate the severity of these deficits; 3) whether ex-opiate users demonstrate smaller decision-making deficits than current users; and 4) whether the length of abstinence is related to the magnitude of decision-making deficits. We analysed 22 studies that compared the performance of current and ex-opiate users to healthy controls on decision-making measures such as the Iowa Gambling Task. Current users demonstrated a moderately strong impairment in decision-making relative to controls, which was not significantly moderated by co-morbid factors. The magnitude of the impairment did not significantly differ between studies assessing current or ex-users, and this impairment was not related to length of abstinence. Thus, it appears that opiate users have relatively severe decision-making deficits that persist at least 1.5 years after cessation of use.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience & Biobehavioral Reviews - Volume 71, December 2016, Pages 342-351
نویسندگان
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