MoO2Cl2 as a novel catalyst for the synthesis of α-aminophosphonates

This work reports the use of MoO2Cl2 as a novel catalyst for the synthesis of α-aminophosphonates. The system HP(O)(OEt)2/MoO2Cl2 (5 mol%) was applied in the synthesis of several α-aminophosphonates in excellent yields under solvent-free conditions.

Graphical AbstractMoO2Cl2 as a novel catalyst for the synthesis of α-aminophosphonates.Figure optionsDownload as PowerPoint slideResearch Highlights
► HP(O)(OEt)2/MoO2Cl2 an excellent catalytic system for the synthesis of α-aminophosphonates.
► High chemoselectivity and yields.
► Solvent-free conditions.