کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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50804 | 46815 | 2011 | 4 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Stereoselective hydroxylation of ethylbenzene to (R)-1-phenylethanol using mycelia of Aspergillus niger as catalyst Stereoselective hydroxylation of ethylbenzene to (R)-1-phenylethanol using mycelia of Aspergillus niger as catalyst](/preview/png/50804.png)
The mycelia of Aspergillus niger MTCC-404 have been shown to act as a biocatalyst for the transformation of ethylbenzene to (R)-1-phenylethanol in 99% enantiomeric excess. 72% of the products are (R)-1-phenylethanol. The conversion yield is dependent on pH, temperature and mycelia concentration in suspension. A. niger MTCC-404 facilitates methylbenzene transformation to benzylalcohol, and propylbenzene to 1-phenylpropanol. Therefore, A. niger serves as a biocatalyst for hydroxylation of alkylbenzene's benzylic position.
Graphical AbstractEthylbenzene has been stereoselectively hydroxylated to (R)-1-phenylethanol using the mycelia of Aspergillus niger MTCC-404 as a biocatalyst.Figure optionsDownload as PowerPoint slideResearch Highlights
► Stereoselective hydroxylation of ethylbenzene has been achieved.
► (R)-1-phenylethanol in 99% enantiomeric execess has been prepared.
► Aspergillus niger MTCC-404 mycelia have been used as a biocatalyst.
► This mycro-organism has a potential for benzylic hydroxylation of alkylbenzenes.
Journal: Catalysis Communications - Volume 12, Issue 9, 30 April 2011, Pages 781–784