کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
50889 | 46820 | 2011 | 4 صفحه PDF | دانلود رایگان |
A simple and efficient procedure for the synthesis of 1, 2-disubstituted benzimidazoles has been developed by a one-pot reaction of o-phenylenediamine with both aromatic and aliphatic aldehydes in the presence of sodium dodecyl sulfate in aqueous medium at room temperature in open air without any organic solvent. The surfactant is recycled. A plausible mechanistic approach has also been suggested.
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► A simple route to 1,2-disubstituted benzimidazoles in water by the use of SDS as catalyst.
► A quick process with a good to excellent yield.
► Less environmental hazard as compared to other reported methods.
► Reusability of the catalyst was noted.
► May be accepted as a potential protocol for industrial application.
Journal: Catalysis Communications - Volume 12, Issue 8, 31 March 2011, Pages 744–747