کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5119907 1486110 2017 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Serious suicide attempts in outpatients with multiple substance use disorders
ترجمه فارسی عنوان
خودکشی جدی در بیماران سرپایی با اختلالات مصرف مواد مختلف تلاش می کند
کلمات کلیدی
اختلالات مصرف مواد، تلاش خودکشی جدی جنسیت، بنزودیازپین، اختلال مصرف دارو، اعتیاد به مواد مخدر،
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
چکیده انگلیسی


- Men and women were at equal risk for serious suicide attempts (SA) in our sample.
- Risk factors for serious SA were mainly gender-specific.
- Sedative dependence increased serious SA risk with slight differences regarding gender.
- Suicidal women may benefit from opiate agonists and antidepressants when indicated.
- We have identified subgroups to target for the prevention of serious SA in addiction.

BackgroundSuicide is a major public health concern and suicide attempts (SA) are frequent and burdensome in people suffering from substance use disorders (SUDs). In particular, serious SAs are a preoccupying form of attempt, which remain largely overlooked in these populations, especially regarding basic risk factors such as gender, addictive comorbidity and substance use patterns. Thus, we undertook a gender-specific approach to identify the risk factors for serious SAs in outpatients with multiple SUDs.Material and methods433 Treatment-seeking outpatients were consecutively recruited in specialized care centers and reliably classified as serious, non-serious and non-suicide attempters. We also characterized lifetime exposure to SUDs, including tobacco smoking, with standardized instruments. Current medication, including psychotropic treatments were collected, which informed psychiatric diagnoses. Multinomial regression identified independent factors specifically associated with serious SAs in each gender, separately.Results32% Participants (N = 139, 47% Women and 27% Men) reported lifetime SA. There were 82 serious attempters (59% of attempters), without significant gender difference. Sedative dependence was an independent risk factor for serious SA compared to non-SA in Women and compared to non-serious SA in Men, respectively. Other risk factors included later onset of daily tobacco smoking in Men and history of psychiatric hospitalizations in Women, whose serious SA risk was conversely lower when reporting opiate use disorder or mood disorder, probably because of treatment issues.ConclusionsDespite several study limitations, we identified subgroups for a better-tailored prevention of serious SAs among individuals with SUDs, notably highlighting the need to better prevent and treat sedative dependence.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Drug and Alcohol Dependence - Volume 181, 1 December 2017, Pages 63-70
نویسندگان
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