کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5121852 | 1486845 | 2017 | 9 صفحه PDF | دانلود رایگان |
ObjectiveAccurate estimation of the true incidence of ill-health is a goal of many surveillance systems. In surveillance schemes including zero reporting to remove ambiguity with nonresponse, reporter fatigue might increase the likelihood of a false zero case report in turn underestimating the true incidence rate and creating a biased downward trend over time.Study Design and SettingMultilevel zero-inflated negative binomial models were fitted to incidence case reports of three surveillance schemes running between 1996 and 2012 in the United Kingdom. Estimates of the true annual incidence rates were produced by weighting the reported number of cases by the predicted excess zero rate in addition to the within-scheme standard adjustment for response rate and the participation rate.ResultsTime since joining the scheme was associated with the odds of excess zero case reports for most schemes, resulting in weaker calendar trends. Estimated incidence rates (95% confidence interval) per 100,000 person years, were approximately doubled to 30 (21-39), 137 (116-157), 33 (27-39), when excess zero-rate adjustment was applied.ConclusionIf we accept that excess zeros are in reality nonresponse by busy reporters, then usual estimates of incidence are likely to be significantly underestimated and previously thought strong downward trends overestimated.
Journal: Journal of Clinical Epidemiology - Volume 81, January 2017, Pages 77-85