Gold complex-catalyzed CP bond formation by Kabachnik–Fields reactions

CP bond formation was realized through the three-component reaction of an amine, an aldehyde and a dialkylphosphite catalyzed by gold complex. The corresponding α-aminophosphonates were afforded in one-pot reaction with high yields under mild conditions.

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► C–P bonds formation was realized through the reaction catalyzed by gold complex.
► Gold-bipy complex show the best catalytic activity.
► Reactions of aldehydes with aromatic amines do not show remarkable difference.
► A plausible mechanism of the reaction is proposed based on some experiments.
► Cleaner conversion, higher yields are some of the advantages of the protocol.