کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5132439 1492052 2018 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Occurrence of antibiotics in mussels and clams from various FAO areas
ترجمه فارسی عنوان
ظهور آنتی بیوتیک ها در گوشت گاو و گوسفند از مناطق مختلف فائو
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی


- A multiclass LC-MS/MS method for 29 antibiotics was developed and validated.
- Our detection limits were much lower than the maximum residue limits.
- Pool of mussels and clams from different FAO zones were analysed.
- Antibiotic presence in the analysed shellfish is negligible.

Filter feeders, like mussels and clams, are suitable bioindicators of environmental pollution. These shellfish, when destined for human consumption, undergo a depuration step that aims to nullify their pathogenic microorganism load and decrease chemical contamination. Nevertheless, the lack of contamination by drugs may not be guaranteed. Antimicrobials are a class of drugs of particular concern due to the increasing phenomenon of antibiotic resistance. Their use in breeding and aquaculture is a major cause of this. We developed a multiclass method for the HPLC-MS/MS analysis of 29 antimicrobials, validated according to the Commission Decision 2002/657/UE guidelines, and applied it to 50 mussel and 50 clam samples derived from various Food and Agricultural Organisation marine zones. The results obtained, indicate a negligible presence of antibiotics. Just one clam sample showed the presence of oxytetracycline at a concentration slightly higher than the European Union Maximum residue limit set for fish.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Food Chemistry - Volume 240, 1 February 2018, Pages 16-23
نویسندگان
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