کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5134155 | 1492073 | 2017 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Fetal bovine serum influences the stability and bioactivity of resveratrol analogues: A polyphenol-protein interaction approach
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Fetal bovine serum influences the stability and bioactivity of resveratrol analogues: A polyphenol-protein interaction approach Fetal bovine serum influences the stability and bioactivity of resveratrol analogues: A polyphenol-protein interaction approach](/preview/png/5134155.png)
چکیده انگلیسی
Fetal bovine serum (FBS) is a universal growth supplement of cell and tissue culture media. Herein, the influences of FBS on the stability and antioxidant activity of 21 resveratrol analogues were investigated using a polyphenol-protein interaction approach. The structure-stability relationships of resveratrol analogues in FBS showed a clear decrease in the stability of hydroxylated resveratrol analogues in the order: resorcinol-type > pyrogallol-type > catechol-type. The glycosylation and methoxylation of resveratrol analogues enhanced their stability. A linear relationship between the stability of resveratrol analogues in FBS and the affinity of resveratrol analogues-FBS interaction was found. The oxidation process is not the only factor governing the stability of resveratrol analogues in FBS. These results facilitated the insightful investigation of the role of polyphenol-protein interactions in serum, thereby providing some fundamental clues for future clinical research and pharmacological studies on natural small molecules.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Food Chemistry - Volume 219, 15 March 2017, Pages 321-328
Journal: Food Chemistry - Volume 219, 15 March 2017, Pages 321-328
نویسندگان
Fen Tang, Yixi Xie, Hui Cao, Hua Yang, Xiaoqing Chen, Jianbo Xiao,