Novel potentially antibacterial naphthalimide-derived metronidazoles: Design, synthesis, biological evaluation and supramolecular interactions with DNA, human serum albumin and topoisomerase II

A series of novel naphthalimide-derived metronidazoles as new antibacterial agents were developed. Relational supramolecular interactions with DNA, human serum albumin and topoisomerase II were investigated for the evaluation of antibacterial potentiality.