A facile method for building fused quinoxaline-quinolinones via an acidless post-Ugi cascade reaction

A series of quinolino[3,4-b]quinoxalin-6(5H)-ones have been synthesized using an Ugi/deprotection/cyclization (UDC) strategy, followed by a nucleophilic aromatic substitution reaction. This scaffold was thought to be a very important intermediate for building bioactive compounds.