Thermoresponsive dendronized copolymers for protein recognitions based on biotin-avidin interaction

Biotinylated dendronized copolymers were synthesized efficiently via free radical copolymerization, and their thermoresponsive properties, as well as thermally-regulated biotin-avidin interaction was investigated. Dendron generation was found to play an important rule on mediating the biotin-avidin interaction with temperature as a switcher.