A heterogeneous strong basic nanocrystalline copper(II) oxide catalyst for efficient synthesis of 4-keto-4,5,6,7-tetrahydrobenzofurans

An efficient synthesis of tetrahydrobenzofurans is carried out in one pot through the reaction of 1,3-diketone and phenacyl bromides compound using a heterogeneous basic nano particles copper oxide catalyst. The protocol offers advantages in terms of higher yields, short reaction times, and mild reaction conditions, with reusability of the catalyst.