Discovery of a novel class of highly potent inhibitors of the p53-MDM2 interaction by structure-based design starting from a conformational argument

Discovery of a novel class of highly potent inhibitors of the p53-MDM2 interaction by structure-based design starting from a conformational argument

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 26, Issue 19, 1 October 2016, Pages 4837-4841

Pascal Furet, Keiichi Masuya, Joerg Kallen, Thérèse Stachyra-Valat, Stephan Ruetz, Vito Guagnano, Philipp Holzer, Robert Mah, Stefan Stutz, Andrea Vaupel, Patrick Chène, Sébastien Jeay, Achim Schlapbach,